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Wednesday 11 June 2008 

Morning Sessions 8.15 – 10.30am 

W1:    Physiological testing interpretation                                              

Hall tbc

Dr R Crapo (USA)                 Dr M Miller (UK)Dr B Cooper (UK) 

W2:      Expert discussion on smoking cessation                                      

Hall tbc

Dr G Wesseling (NL)             Dr P Tonnesen (Den)       Open debate 

W3:      Nasal ventilation in COPD                                                              

Hall tbc

8.15      NIV for COPD acute and chronic - patient selection, the evidence   

Dr M Elliott (UK)

8.45      Interfaces

Mr M Latham (UK)

9.15      Setting the ventilator and troubleshooting

- how does an understanding of physiology help 

Dr P Navalesi (Italy)

9.55      Panel discussion 

W4:     

Hall tbc

Part 1: Developing the skills of the multidisciplinary team   

Prof S Hill (UK)K Walker (UK)                                                                                                                                               

Part 2: Developing the expert patient                                                          

Dame H Shovelton (UK)     

10.30 – 11.00am         Refreshment Break                                                    

Hall 3   11.00 – 1.00pm

PS1: OPENING PLENARY                                                                                  

Hall 1

Management of the COPD patient 1 -what clinical trials are telling us

Chairpersons: Prof P Calverley (UK) & Prof S Rennard (USA)           

11.00    Welcome

11.05    Mortality and co-morbid conditions                                                          

Prof S Rennard (USA)

11.25    Exacerbations, their treatment, and pneumonia                                        

Prof J A Wedzicha (UK)

11.45    Lessons from alpha-1 antitrypsin augmentation                                         Prof A Dirksen (Den) Prof R Stockley (UK)12.25    Do we have adequate models of COPD?                                                    Prof G Anderson (Aus)12.45    Presentation of Lifetime Achievement Awards                      1.00 – 2.00pm Lunch and Poster Viewing                                          Hall 3 
Wednesday 11 June 2008 Afternoon Sessions 2.00 – 3.30pm PS2: Management of the COPD patient 2 – Impact of co-morbidities           Hall 1Chairperson: Prof L Fabbri (Italy)2.00      What is the clinical evidence?                                                      Prof L Fabbri (Italy)2.20      What are the genetics of co-morbidity                                          Prof R Stockley (UK)       2.40      COPD and vascular disease                                                         Prof E Wouters (NL)3.00      COPD and osteoporosis                                                               Prof D Shale (UK)3.20      Implications for management                                                      Panel discussion 3.30 – 4.00pm Refreshment Break                                                     Hall 3 4.00 – 5.30pm SS1: Patient focused outcomes - how should we measure and validate them         Hall tbcChairpersons: Prof P Meek (USA) & Prof S Hill (UK)4.00      Concept of patient focused outcomes                                          Prof P Meek (USA)4.15      Measurement & validation, concepts, where we've got it right and where we need to go                                                           Prof P Jones (UK)4.30      Functional status and symptoms-why we measure them pros/cons of measurement                                                          S Lareau (USA)              4.45      How can we validate self management strategies?                        Prof M Partridge (UK)5.00      Exacerbation outcomes                                                               Prof R Stockley (UK)5.15      Discussion  SS2: Patient phenotyping – implications for genetic studies and treatment            Hall tbcChairpersons: Prof D Lomas (UK) & Dr E Silverman (USA)4.00      The role of IOS in COPD                                                  Prof P Calverley (UK)4.20      CT phenotypes of COPD                                                  Dr D Parr (UK)4.40      Sputum analysis in COPD                                                            Dr I Pavord (UK)5.00      Genetic analysis and sub-phenotypes of COPD                               Dr E Silverman (USA)  SS3: Pathophysiology 2008 update                                                                            Hall tbcChairpersons: Prof A Agusti (Spain) & Prof W MacNee (UK)4.00      Inflammation: structure-function relationships                               Prof J Hogg (Canada)4.20      Mechanisms of enhanced inflammation                                         Prof W MacNee (UK)4.40      Mechanisms of persistence of inflammation                                  Prof A Agusti  (Spain)5.00      Overview: a lung maintenance programme                                   Prof N Voelkel (USA)  5.45 – 6.45pmMajor Sponsors Symposium                BI/Pfizer Symposium               Hall 1 Earlier intervention in COPD: rationale and benefitsChairman: Dr C Vogelmeier (Germany)            5.45      Welcome and brief introduction to the natural history                        and burden of COPD                                                                   Dr C Vogelmeier (Germany)            6.00      Can we impact the clinical course of COPD?                                  Dr C Cooper (USA)            6.20      Earlier intervention in COPD – why wait?                                       Prof M Decramer (Belgium)            6.40      Questions, summary and close    Thursday 12 June 2008 Morning Sessions 8.00 – 10.00am PS3: Acute care - Exacerbations                                                                    Hall 1Chairpersons: Prof J A Wedzicha & Prof F Martinez8.00         Etiology of COPD exacerbations                                                    Prof A Papi (Italy)8.30         Mechanisms of inflammation in COPD exacerbations                      Prof Peter Barnes (UK)9.00         Experimental models of COPD exacerbations                                 Dr P Mallia (UK)9.30         Novel approaches to prevention of COPD exacerbations                  Prof J A W Wedzicha (UK)  10.00 – 10.30am         Refreshment Break                                                     Hall 3  10.30 – 12.00 noonSS4: End of life care for COPD – a new approach?                                         Hall tbcChairpersons: Dr M Morgan (UK) & S Prigmore (UK)10.30       Definition of End of life                                                                Dr N O'Kelly (UK)10.45       Patient needs                                                                             Dr P White (UK)11.00       Palliative treatment options                                                         Prof S Ahmedzai (UK)11.15       Withholding, withdrawal, ceilings of treatment                              Dr A Simonds (UK)11.30       Liverpool End of Life care pathway                                               Dr L Davies (UK)  SS5: Role of antibiotics for both prophylaxis and therapeutic use   Hall tbcChairpersons: Dr R Wilson (UK) & Prof F Blasi (Italy)10.30       Does a “bronchiectasis-like” vicious circle operate in COPD?            Dr R Wilson (UK)10.50       Antibiotic prophylaxis in COPD (including the PULSE study)  Dr M Miravitlles (Spain)11.10       Antibiotic trials in COPD: placebo or superiority design?                  Prof F Blasi (Italy)11.30       Are macrolides the answer for COPD?                                          Prof J A Wedzicha (UK)  SS6: Muscle loss in COPD, reactive or causative?                                          Hall tbcChairpersons: Prof M Polkey (UK) & Prof M Decramer (Belgium)10.30       Overview and scope of the problem                                             Prof M Polkey (UK)10.50       Muscle strength and daily activity                                     Prof M Decramer (Belgium)11.10       Signaling pathways that mediate skeletal muscle atophy                Dr David Glass (USA)11.30       Nutritional strategies for muscle weakness                                    Prof A Schols (NL)  12.00 – 1.00pm           Meet the ExpertsNursing research – is it practical, what does it need to focus on                     Prof P Meek (USA)Selection for transplantation and management                                             Prof P Corris (UK)Bronchiectasis and COPD : the chronically colonised patient               Dr R Wilson (UK)Research funding – practical advice on applying to MRC, BLF, Wellcome         Prof E Chilvers (UK)   1.00 – 2.00pm Lunch and Poster Viewing                                          Hall 3  
Thursday 12 June 2008 Afternoon Sessions 2.00 – 4.00pm PS4: Chronic care - Getting the patient going                                   Hall 1Chairpersons: Prof J A Wedzicha (UK) & Prof M Decramer (Belgium)                                               2.00         Rationale                                                                      Prof M Decramer (Belgium) 2.15         Activity, co-morbidities and rehabilitation                          Prof T Troosters (NL) 2.35         Pulmonary Rehabilitation and exacerbation – when is the right time to intervene                                Prof M Polkey (UK) 2.55         Who should instigate rehabilitation?                                 Prof R Jones (UK) 3.15         Questions                                                                                         “Tim Griffiths Memorial Lecture” 3.30         Introduction                                                                   Adjuncts to rehabilitation                                     Prof R Casaburi (USA)   4.00 – 4.30pm Refreshment Break                                                     Hall 3  4.30 – 6.00pmSS7: Standards for COPD care – can we get them into practice                   Hall tbcChairpersons: Prof S Hill (UK) & Prof S Buist (USA)4.30         What do we need standards for and what can we learn?                Prof S Buist (USA)4.50         Establishing national standards                                                    Prof S Hill (UK) 5.10         Do guidelines help?                                                                     Prof P Calverley (UK)5.30         How can standards be monitored?                                               Prof M Pearson (UK) SS8: Practically reducing mortality in COPD; what is science telling us         Hall tbcChairpersons: Prof F Martinez (USA) & Dr M Miller (UK)4.30         FEV1 and mortality                                                         Dr M Miller (UK)4.50         Treatments that reduce mortality                         Prof B Celli (USA)5.10         Why treatment reduces mortality                         Prof F Martinez (USA)5.30         Smoking cessation                                                          Prof S Rennard (USA)  SS9: Realising the benefits of new therapeutic developments                     Hall tbcChairpersons: Prof P Barnes (UK) & Dr T Hansel (UK)4.30         How should new anti-inflammatory drugs for COPD first be tested in man ?                                                                          Dr T Hansel (UK)4.50         Novel antioxidants – where are they when we need them? Prof W MacNee (UK)5.10         Reversing steroid resistance – a new approach                             Prof P Barnes (UK)5.30         Antiproteases – why has it taken so long?                         Prof R Stockley (UK)  
Friday 13 June 2008 7.45 – 8.45am Meet the ExpertsPractical considerations of oxygen assessment & therapy                  C Mikelsons (UK)Alpha one anti-trypsin deficiency – where are we now?                     Prof R Stockley (UK)Sleep in COPD                                                                               Dr B Cooper (UK)Nursing – open discussion                                                              S Prigmore (UK)  9.00 – 10.30SS10: Helping you to help your COPD patient                                                Hall tbcChairpersons: Prof D Price (UK)       9.00         Models of improving practice management of COPD                       Dr J Cleland (UK)9.20         Software tools to assist in assessing the patient with COPD            Dr R Jones (UK)9.40         Helping physicians with virtual COPD reviews                                Prof D Price (UK)10.00       Using the web and other self-help tools to assist in COPD management                                                                             Dr Rob Horne (UK)  SS11: Differential diagnosis                                                                            Hall tbcChairperson: Prof R Stockley (UK)9.00         Causes of breathlessness – a clinical algorithm                             Prof Paul Corris (UK)9.20         How should we characterise COPD and prevent misdiagnosis          Prof W MacNee (UK)9.40         Early detection & management of malignancy in COPD                   Prof S Spiro (UK)10.00       Does phenotype influence management?                          Prof B Celli (USA)  SS12: Lung protection / repair – can it be done?                                          Hall tbcChairpersons: Prof G Anderson (Aus) & Prof S Rennard (USA)9.00         Animal models – role of TNFa                                                     Dr A Churg (USA)9.20         Why doesn’t anti-TNFa work?                                                      Prof S Rennard (USA)9.40         Retinoic acid receptor g                                                               Prof G Anderson (Aus)10.00       Repair strategy                                                                          Dr J Stolk (NL)  10.30 – 11.00am                     Refreshment Break                                         Hall 1 Foyer  11.00 – 1.00pmPS5: FINAL INTERACTIVE PLENARY                                                                  Hall 1Practicalities, barriers and opportunities in delivering COPD care 11.00       What is epidemiology telling us?                                                  Prof S Buist (USA) 11.30       Primary care perspective                                                             Prof D Price (UK) 11.40       Role of the specialist – achieving integration                                             Prof B Celli (USA) 11.50       Can we get self-management strategies right?                                          Prof M Partridge (UK) 12.00       Can we / should we introduce screening for the missing millions?               Prof P Calverley (UK) 12.10       Interactive discussion with audience                                                         V Parry              12.50       Closing Remarks                                                            Prof S Hill (UK) & Prof R Stockley (UK) 

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